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Identification of PI3 kinase-dependent activators of rac
Reference
BBS/E/B/52976411
Principal Investigator / Supervisor
Dr Phillip Hawkins
Co-Investigators /
Co-Supervisors
Institution
Babraham Institute
Department
Babraham Institute Department
Funding type
Research
Value (£)
117,744
Status
Completed
Type
Institute Project
Start date
01/01/1999
End date
31/12/2005
Duration
84 months
Abstract
We wish to understand more clearly how white cells can fight certain types of infection. In particular we are studying how bacterially-derived protein fragments stimulate neutrophils in the blood to generate toxic oxygen metabolites which are used to kill engulfed bacteria. This process is necessary to combat bacterial infections but may be stimulated inappropriately during certain pathological inflammatory conditions, such as asthma and arthritis.
Summary
unavailable
Committee
Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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