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Vav, the cytoskeleton and cell motility
Reference
BBS/E/B/31966435
Principal Investigator / Supervisor
Dr Martin Turner
Co-Investigators /
Co-Supervisors
Institution
Babraham Institute
Department
Babraham Institute Department
Funding type
Research
Value (£)
96,310
Status
Completed
Type
Institute Project
Start date
01/01/1999
End date
30/12/2002
Duration
48 months
Abstract
Abnormal cell migration is a feature of human tumours which would be desirable to inhibit. Vav is a protein which may regulate migration in lymphocytes. We propose to study the migratory abilities of lymphocytes from Vav-/- mice. If defects are found and their basis characterised, inhibitors of Vav may be useful to block tumour cell migration. The recent findings of Vav homologs in cell types other than lymphocytes suggests the findings on Vav and cell motility will have impact in cell types other than lymphocytes.
Summary
unavailable
Committee
Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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