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Molecular mechanisms in CTLA-4 signal transduction in human T cells

Reference	BBS/E/B/31917425
Principal Investigator / Supervisor	Dr Denis Alexander
Co-Investigators / Co-Supervisors
Institution	Babraham Institute
Department	Babraham Institute Department
Funding type	Research
Value (£)	52,340
Status	Completed
Type	Institute Project
Start date	15/04/1999
End date	14/04/2002
Duration	36 months

Abstract

T cells are white blood cells which play a central role in fighting disease. Some receptors on the surface of T cells deliver powerful negative signals to the cell. This project aims to understand how these negative signals work and how they might be used in the control of diseases which are caused when these pathways do not function correctly, in particular auto- immune diabetes, EAE and asthma.

Summary

unavailable

Committee	Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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