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The role of CD45 isoforms in T-cell signalling in cell-lines

ReferenceBBS/E/B/31001136
Principal Investigator / Supervisor Dr Denis Alexander
Co-Investigators /
Co-Supervisors
Institution Babraham Institute
DepartmentBabraham Institute Department
Funding typeResearch
Value (£) 1,122,044
StatusCompleted
TypeInstitute Project
Start date 01/04/1998
End date 31/03/2003
Duration60 months

Abstract

T cells are white blood cells which play a central role in fighting off disease. CD45 is a molecule found on the surface of T cells in different forms. This project aims to use cell-lines to find out how these different forms of CD45 regulate signals inside the cells. The investigation is important for understanding how to use antibodies against CD45 isoforms as therapeutic reagents.

Summary

unavailable
Committee Closed Committee - Biochemistry & Cell Biology (BCB)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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