BBSRC Portfolio Analyser
Award details
Lipid droplets as dynamic organelles of fat deposition and release: translational research towards human disease
Reference
BBS/E/B/0000S227
Principal Investigator / Supervisor
Professor Michael Wakelam
Co-Investigators /
Co-Supervisors
Institution
Babraham Institute
Department
Babraham Institute Department
Funding type
Research
Value (£)
152,334
Status
Completed
Type
Institute Project
Start date
01/09/2008
End date
31/08/2012
Duration
48 months
Abstract
Lipid droplets store lipids (fats) within cells, particularly in adipose (body fat) and liver tissue. Disorders such as metabolic syndrome and type 2 diabetes are associated with excessive lipid droplet synthesis, this is further complicated by such droplets inside the cell potentiating replication of hepatitis C virus. This large multicentre project integrates studies upon human and mouse examples and on cell line models in order to understand how droplet biosynthesis and turnover is regulated. The work involves gene expression (the copying of DNA into RNA and then often into protein) studies and proteomic (cell protein) and lipidomic analysis.
Summary
unavailable
Committee
Not funded via Committee
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search