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Molecular mechanism of action of a humanised antibody on T cell immunosuppression

Reference	BBS/E/B/0000O066
Principal Investigator / Supervisor	Dr Denis Alexander
Co-Investigators / Co-Supervisors
Institution	Babraham Institute
Department	Babraham Institute Department
Funding type	Research
Value (£)	22,347
Status	Completed
Type	Institute Project
Start date	01/04/2003
End date	31/12/2004
Duration	21 months

Abstract

Therapeutic antibodies are being used in clinical trials for autoimmune diseases such as psoriasis and rheumatoid arthritis. In this project we are aiming to find out how a particular antibody works, in particular how it affects the responses of T cells in such a way that they no longer contribute to inappropriate immune responses.

Summary

unavailable

Committee	Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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