Award details

MRC DTA Studentship: The Cellular Role of the Gimap (Ian) GTPases

Reference	BBS/E/B/0000M985
Principal Investigator / Supervisor	Dr Geoff Butcher
Co-Investigators / Co-Supervisors
Institution	Babraham Institute
Department	Babraham Institute Department
Funding type	Research
Value (£)	145,625
Status	Completed
Type	Institute Project
Start date	01/10/2005
End date	30/09/2009
Duration	48 months

Abstract

Different types of white blood cells, including lymphocytes and macrophages, work together to defend us from infectious organisms and toxic substances. In the course of the active responses that these cells make they go through rounds of cell division and in so doing can increase their numbers substantially. Later, when the danger has passed, many of these cells die as the population returns to its starting size. There is only a limited understanding of the way in which cell population size is controlled. There is evidence that the Gimap (or Ian) genes, which code for a small family of signalling molecules, participate in the processes that establish white blood cell population. This project aims to discover more about the Gimap proteins and their precise cellular roles, particularly in respect of T lymphocyte function.

Summary

unavailable

Committee	Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics	Immunology
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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