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Award details
MRC Capacity Building Studentship: Defining the function of new genes in the immune system
Reference
BBS/E/B/0000M983
Principal Investigator / Supervisor
Dr Martin Turner
Co-Investigators /
Co-Supervisors
Institution
Babraham Institute
Department
Babraham Institute Department
Funding type
Research
Value (£)
141,186
Status
Completed
Type
Institute Project
Start date
01/10/2005
End date
30/09/2009
Duration
48 months
Abstract
A biochemical and genetic understanding of the signals delivered by antigen receptors of lymphocytes will lead to the identification of novel targets for small molecule inhibitors or activators of immune function. For example, considerable interest in understanding the role of post-transcriptional control in antigen receptor regulation of cytokine expression or lymphocyte differentiation may contribute to new strategies to deal with allergic or autoimmune diseases. Understanding why the peripheral B cell pool is stably maintained at about 100 million cells which represents only a tiny fraction of the potential antibody has important consequences for immunity and the generation of the antibody repertoire.
Summary
unavailable
Committee
Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics
Immunology
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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