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MRC Quota Studentship: Structural and functional aspects of cadherins in cell adhesion
Reference
BBS/E/B/0000M930
Principal Investigator / Supervisor
Dr Peter Kilshaw
Co-Investigators /
Co-Supervisors
Institution
Babraham Institute
Department
Babraham Institute Department
Funding type
Research
Value (£)
20,717
Status
Completed
Type
Institute Project
Start date
01/10/2001
End date
31/10/2006
Duration
61 months
Abstract
The cadherin family is one of the most important groups of cell adhesion molecules. Cadherins play a vital role in the development and correct functioning of all tissues. Aberration of cadherin-mediated cell adhesion is a central cause of cancer metastasis. This laboratory is studying the mechanisms by which cells control the adhesive capacity of cadherins on their surface. We are applying a novel molecular approach involving antibodies which will detect shape changes in the cadherin molecules as their adhesive capacity is modulated by the cell.
Summary
unavailable
Committee
Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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