BBSRC Portfolio Analyser
Award details
MRC DTG studentship: Role of transcriptional events in establishment of imprinted methylation
Reference
BBS/E/B/0000M724
Principal Investigator / Supervisor
Dr Gavin Kelsey
Co-Investigators /
Co-Supervisors
Institution
Babraham Institute
Department
Babraham Institute Department
Funding type
Research
Value (£)
150,507
Status
Completed
Type
Institute Project
Start date
01/10/2007
End date
30/09/2011
Duration
48 months
Abstract
We inherit a set of genes from our mother and our father. For most genes, both copies are equally active, irrespective of parentage. A few genes defy this rule, one copy being silenced by a process that begins in the germ cells - the cells that will combine to form the embryo at fertilisation - and these are called imprinted genes. Imprinted genes have particularly important roles in how the fetus grows and develops. We are investigating how imprinted genes are marked in this way in the egg cell. It is important that these marks are laid down correctly. Mistakes in this process that could occur because of environmental factors or through procedures like assisted reproduction technologies may not be corrected in the fetus and may lead to developmental abnormalities or an increased risk of disease in later life.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search