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Role of imprinted XLalphaS in postnatal physiology and its interaction with Gs-alpha

ReferenceBBS/E/B/0000M147
Principal Investigator / Supervisor Dr Gavin Kelsey
Co-Investigators /
Co-Supervisors
Institution Babraham Institute
DepartmentBabraham Institute Department
Funding typeResearch
Value (£) 110,364
StatusCompleted
TypeInstitute Project
Start date 01/04/2005
End date 31/07/2008
Duration40 months

Abstract

We inherit similar sets of genes from both our parents. A small number of genes are different in that one of the two copies is silenced; these are called imprinted genes. This silencing appears to be an important means of controlling these genes¿ activities and seems to be important in helping to control some of our bodies key processes, such as regulating food intake, regulating blood sugar levels and the amount we store as fat. Because imprinted genes have only one active copy, it is particularly important that we understand how they work and the consequences of losing this single active copy.

Summary

unavailable
Committee Closed Committee - Genes & Developmental Biology (GDB)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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