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BBSRC Quota Studentship: Role of P21 in myogenesis: implications for cell cycle exit and myocyte apoptosis
Reference
BBS/E/B/0000L957
Principal Investigator / Supervisor
Dr Jennifer Pell
Co-Investigators /
Co-Supervisors
Institution
Babraham Institute
Department
Babraham Institute Department
Funding type
Research
Value (£)
9,408
Status
Completed
Type
Institute Project
Start date
01/10/2003
End date
30/09/2006
Duration
36 months
Abstract
Muscle development is largely complete before birth. Muscle is formed when committed but undifferentiated cells (called myoblasts) start to produce muscle-specific proteins and fuse to become myofibres. These myofibres will therefore contain many nuclei and are arranged as long, thin and large cells which span the length of the muscle. Muscle fibre number is therefore largely fixed at birth and subsequent muscle growth can only occur by each fibre becoming larger (hypertrophy). Whole body growth rate is correlated with primary myofibre number and therefore it is important to understand the mechanisms which determine fibre number.
Summary
unavailable
Committee
Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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