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BBSRC Quota Studentship: The molecular basis of the interaction of phosphatidylinositol 4-phosphate 5-kinase with phosphatidic acid

ReferenceBBS/E/B/0000L951
Principal Investigator / Supervisor Dr Nicholas Ktistakis
Co-Investigators /
Co-Supervisors
Institution Babraham Institute
DepartmentBabraham Institute Department
Funding typeResearch
Value (£) 21,252
StatusCompleted
TypeInstitute Project
Start date 30/06/2003
End date 31/12/2006
Duration42 months

Abstract

The interaction of cellular proteins with lipid membranes is an important question in Biology primarily because such interactions determine the correct subcellular localisation and activity of cellular proteins. In this project we will extend previous observations that showed that phosphatidylinositol 4-phosphate 5-kinase (PIPkin), a protein involved in secretion, cytoskeletal rearrangements and neurotransmitter release is a specific binding partner of phosphatidic acid, a signalling lipid. This information will be useful in understanding the cellular function of PIPkin.

Summary

unavailable
Committee Closed Committee - Biochemistry & Cell Biology (BCB)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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