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Babraham European studentship: Recruiting genes to transcription factories
Reference
BBS/E/B/0000L752
Principal Investigator / Supervisor
Dr Peter Fraser
Co-Investigators /
Co-Supervisors
Institution
Babraham Institute
Department
Babraham Institute Department
Funding type
Research
Value (£)
60,428
Status
Completed
Type
Institute Project
Start date
01/10/2009
End date
30/09/2012
Duration
36 months
Abstract
The expression of genes to make RNA is carried out by a special molecular machine known as RNA polymerase. RNA polymerase copies the information in genes by the process of transcription. Previously it was thought that RNA polymerase molecules visited each of the thousands of active genes in a cell to express them. However, recent data suggests that RNA polymerase molecules are grouped together in transcription factories and that active genes must move to these sites to be transcribed. In this project we will use new fluorescent tagging techniques to visualize genes and the activity of RNA polymerase in live cells. This will allow us to directly visualize who is moving, the genes or the machinery to express them.
Summary
unavailable
Committee
Not funded via Committee
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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