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BBSRC DTG Studentship: Characterising the role of RhoG in the activation of the neutrophil NADPH oxidase
Reference
BBS/E/B/0000L714
Principal Investigator / Supervisor
Dr Phillip Hawkins
Co-Investigators /
Co-Supervisors
Institution
Babraham Institute
Department
Babraham Institute Department
Funding type
Research
Value (£)
139,228
Status
Completed
Type
Institute Project
Start date
01/10/2007
End date
30/09/2011
Duration
48 months
Abstract
This proposal is aimed at understanding some fundamental principles of how neutrophils (a type of white blood cell) might damage host tissue during inflammation. Neutrophils are our first line of defence against bacterial and fungal infections but sometimes they attack the body with the same weapons they use to kill the pathogens, contributing to the damaging effects of many inflammatory diseases, such as acute respiratory distress syndrome (ARDS) and rheumatoid arthritis (RA). The factors which dictate whether neutrophils cause a problem in inflammation are not fully understood and hence it’s currently difficult to know how to inhibit them specifically.
Summary
unavailable
Committee
Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics
Immunology
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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