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BBSTC DTA Studentship: Lysophospholipid signalling via cloned Drosophila G-protein coupled receptors
Reference
BBS/E/B/0000L706
Principal Investigator / Supervisor
Dr Peter Evans
Co-Investigators /
Co-Supervisors
Institution
Babraham Institute
Department
Babraham Institute Department
Funding type
Research
Value (£)
26,433
Status
Completed
Type
Institute Project
Start date
01/10/2006
End date
06/07/2007
Duration
9 months
Abstract
Lysophospholipids, such as lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) are important regulators of a range of cellular processes such as cell growth, differentiation, survival, motility and cytoskeletal reorganisation. An analysis of the genome of the model organism, Drosophila, has revealed the existence of novel genes that are structurally similar to vertebrate Lysophospholipid receptors. This project aims to clone and characterise these receptors in terms of their pharmacology and mode of action. It will increase our basic knowledge of how cells in nervous systems"talk" to each other.
Summary
unavailable
Committee
Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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