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In vivo analysis of lipid phosphate phosphohydrolase function in Drosophila photoreceptors

ReferenceBBS/E/B/0000L146
Principal Investigator / Supervisor Professor Raghu Padinjat
Co-Investigators /
Co-Supervisors
Institution Babraham Institute
DepartmentBabraham Institute Department
Funding typeResearch
Value (£) 93,442
StatusCompleted
TypeInstitute Project
Start date 01/02/2006
End date 31/01/2009
Duration36 months

Abstract

In order to detect and respond to changes in their environment, animal cells have to "signal" these changes from the surface to the interior of the cell. These changes include the detection of light, smell, sound, temperature and vibrations. This process is referred to as signal transduction and is essential for an animal to survive successfully in its environment. Signal transduction consists of a number of chemical reactions involving the organic constituents of the cell membrane. Our work is aimed at understanding the control of a very important component of these chemical reactions. The ultimate use of our understanding of normal animal physiology is that the findings should help us treat animal/human diseases in which these chemical reactions are defective and hence improve the quality of life for such individuals. Examples of such diseases include hereditary blindness and deafness. Axons are the long processes that link neurons together within our brain, spinal cord and peripheral nervous system, allowing neurons to communicate rapidly with one another.

Summary

unavailable
Committee Closed Committee - Biochemistry & Cell Biology (BCB)
Research TopicsNeuroscience and Behaviour
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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