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PhD studentship: Role of PI3K in autoimmunity and infection

ReferenceBBS/E/B/0000H260
Principal Investigator / Supervisor Professor Klaus Okkenhaug
Co-Investigators /
Co-Supervisors
Institution Babraham Institute
DepartmentBabraham Institute Department
Funding typeResearch
Value (£) 26,682
StatusCompleted
TypeInstitute Project
Start date 08/08/2010
End date 07/08/2014
Duration48 months

Abstract

Autoimmune diseases such as Rheumatoid arthritis, systemic lupus erythematosus and multiple sclerosis can be caused by the immune system which instead of fighting pathogens, turns on different organs in the body. The aim of this project is to determine if inhibition of an enzyme called PI3K p110delta can be used to alleviate autoimmunity. At the same time, we will determine if inhibition of p110delta increases risk of infection with common bacteria. These studies will help determine whether p110delta is a good drug target.

Summary

unavailable
Committee Not funded via Committee
Research TopicsImmunology, Pharmaceuticals
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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