Award details

Natural immunity to haematopoietic cells - An opportunity for cellular therapy of cancer

Reference	BBS/E/B/0000H160
Principal Investigator / Supervisor	Professor Francesco Colucci
Co-Investigators / Co-Supervisors
Institution	Babraham Institute
Department	Babraham Institute Department
Funding type	Research
Value (£)	121,739
Status	Completed
Type	Institute Project
Start date	01/07/2005
End date	30/06/2008
Duration	36 months

Abstract

Natural Killer (NK) lymphocytes are white blood cells that spontaneously attack virally infected and malignant cells. They can also naturally react against transplanted blood cells. These are important qualities that can be exploited in the clinics to improve treatment of leukaemia and bone marrow transplantation. However we do not fully understand precisely how NK cells are triggered in these situations. Our research aims at understanding the molecular switch that control NK cells activation during bone marrow transplantation and leukaemia. A better characterisation of these pathways will provide a rational basis to improve cures for cancer.

Summary

unavailable

Committee	Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics	Immunology
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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