BBSRC Portfolio Analyser
Award details
Does the P110d isoform of the enzyme P13-K play a major role in leukaemia and lymphoma?
Reference
BBS/E/B/0000H154
Principal Investigator / Supervisor
Dr Martin Turner
Co-Investigators /
Co-Supervisors
Institution
Babraham Institute
Department
Babraham Institute Department
Funding type
Research
Value (£)
11,099
Status
Completed
Type
Institute Project
Start date
01/06/2005
End date
31/05/2006
Duration
12 months
Abstract
Many cancers that arise in lymphocytes display significant changes in the mechanisms through which cells sense and respond to normal stimuli. Indeed, some lymphoid malignancies can be defined on the basis of the mechanisms which are dysfunctional. One important mechanism controlling malignancy is the P13-K enzyme system. We propose to test the hypothesis that the haematopoietic restricted P13-K isoform is a major contributor to lymphoid malignancy. If this is proven it paves the way for the use of specific modulators of this enzyme in malignancy.
Summary
unavailable
Committee
Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search