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Mechanism of axonal mitochondrial transport and quality control: impact on neuronal homeostasis and neurodegeneration
Reference
BBS/E/B/0000H118
Principal Investigator / Supervisor
Professor Michael Philip Coleman
Co-Investigators /
Co-Supervisors
Institution
Babraham Institute
Department
Babraham Institute Department
Funding type
Research
Value (£)
11,970
Status
Current
Type
Institute Project
Start date
01/10/2011
End date
30/09/2015
Duration
48 months
Abstract
Recently a novel mechanism was proposed for Parkinson’s disease which also has important implications for how mitochondria are maintained during normal ageing. However, the mechanism was worked out in a non-neuronal cell line. The aim of this project is to understand mechanisms by which mitochondria are maintained during ageing in neurons, and most specifically in their axons.
Summary
unavailable
Committee
Not funded via Committee
Research Topics
Ageing, Neuroscience and Behaviour
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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