BBSRC Portfolio Analyser
Award details
Gates Trust Studentship:The role of PIP2 in drosophila phototransduction
Reference
BBS/E/B/0000F968
Principal Investigator / Supervisor
Professor Raghu Padinjat
Co-Investigators /
Co-Supervisors
Institution
Babraham Institute
Department
Babraham Institute Department
Funding type
Research
Value (£)
20,899
Status
Completed
Type
Institute Project
Start date
01/10/2003
End date
30/09/2006
Duration
36 months
Abstract
Numerous human and animal diseases arise from defective ¿signal transduction¿, the internal chemical language that cells use to monitor their surroundings and talk to other cells. An outstanding question in signal transduction is the strategy that cells use to maintain the fidelity of signal transmission whilst using relatively few chemical components to perform multiple functions. Studies in ¿model organisms¿ are a powerful approach to understand the genetic basis of genetic & molecular basis of signal transduction. The fruit fly Drosophila is a powerful model system for understanding these questions. Although relatively simple but apparently very different from higher animals, numerous studies have established that the fundamental logic of cellular signal transduction is conserved between flies and humans. This multidisciplinary project seeks to understand how flies are able to use the same chemical components to detect light as well as mediate numerous other cellular functions. In addition to addressing a fundamental scientific question, in the long run the results are likely to help design therapeutics with fewer side effects for diseases in which defects in signal transduction play a key role
Summary
unavailable
Committee
Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search