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Reconstitution of autophagy in vitro
Reference
BBS/E/B/0000C341
Principal Investigator / Supervisor
Dr Nicholas Ktistakis
Co-Investigators /
Co-Supervisors
Institution
Babraham Institute
Department
Babraham Institute Department
Funding type
Research
Value (£)
97,479
Status
Completed
Type
Institute Project
Start date
03/01/2012
End date
02/01/2014
Duration
24 months
Abstract
Autophagy (meaning self-digestion) is an important function of healthy cells that allows them to remove faulty membranes and to replenish some nutrients when their external supply is compromised. The vesicle that mediates autophagy is called an autophagosome and it forms rapidly in cells once the trigger has been created. Although many components are known required for forming autophagosomes, the way they organise themselves and their precise roles are not known. The aim of this work will be to start to understand how autophagy proteins form an autophagosome.
Summary
unavailable
Committee
Not funded via Committee
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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