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Role and mechanisms of gene silencing and heterochromatin in lymphocyte development
Reference
BBS/E/B/0000C338
Principal Investigator / Supervisor
Dr Patrick Varga-Weisz
Co-Investigators /
Co-Supervisors
Dr Anne Corcoran
Institution
Babraham Institute
Department
Babraham Institute Department
Funding type
Research
Value (£)
41,300
Status
Completed
Type
Institute Project
Start date
26/09/2011
End date
25/09/2012
Duration
12 months
Abstract
For normal cell function, it is equally important to switch on and switch off the correct genes in the correct cells. We have discovered an important factor, Smarcad1, that switches of large parts of the genome in cells where this is necessary. In this project we will remove this factor in B and T cells which are the major cells that fight infection in the body. We will determine what role this factor plays in helping these cells to perform their specialized functions, in particular which genes are switched off by Smarcad1.
Summary
unavailable
Committee
Not funded via Committee
Research Topics
Immunology
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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