Award details

Phospholipase D signalling

Reference	BBS/E/B/0000C227
Principal Investigator / Supervisor	Professor Michael Wakelam
Co-Investigators / Co-Supervisors
Institution	Babraham Institute
Department	Babraham Institute Department
Funding type	Research
Value (£)	2,211,906
Status	Completed
Type	Institute Project
Start date	01/01/2007
End date	31/03/2012
Duration	63 months

Abstract

Cells communicate through the activation of cell surface receptors (a protein that binds to specific molecules). This communication regulates processes such as cell division, survival, migration, differentiation (specialisation), metabolism and contraction. These diverse processes are regulated by a number of signalling pathways in the cell. Considerable research has identified many of these pathways, however, their regulation and the detail of how they control physiological processes remains sketchy. In this project we focus upon pathways regulating the generation of the lipid (fat) messengers phosphatidic acid and lysophosphatidic acid and upon their molecular targets.

Summary

unavailable

Committee	Closed Committee - Biochemistry & Cell Biology (BCB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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