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Paternal Antigens, Maternal Killer Lymphocytes, and Reproduction
Reference
BBS/E/B/0000C225
Principal Investigator / Supervisor
Dr Myriam Hemberger
Co-Investigators /
Co-Supervisors
Professor Francesco Colucci
Institution
Babraham Institute
Department
Babraham Institute Department
Funding type
Research
Value (£)
201,461
Status
Completed
Type
Institute Project
Start date
01/10/2006
End date
30/09/2009
Duration
36 months
Abstract
During pregnancy, the developing foetus expresses paternal surface antigens, yet it is normally not recognized by the mother as a foreign tissue graft and is not rejected. Instead the maternal immune system is 'reprogrammed' during pregnancy and is tolerant towards the foetus. This project investigates how maternal immune cells and foetal cells of the placenta interact on the molecular level to achieve a mutually beneficial partnership between mother and foetus that is essential for the success of pregnancy.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
Immunology, Stem Cells
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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