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Regulation of superoxide formation

ReferenceBBS/E/B/0000C218
Principal Investigator / Supervisor Dr Phillip Hawkins
Co-Investigators /
Co-Supervisors
Institution Babraham Institute
DepartmentBabraham Institute Department
Funding typeResearch
Value (£) 1,308,847
StatusCompleted
TypeInstitute Project
Start date 01/04/2008
End date 31/03/2012
Duration48 months

Abstract

White blood cells are responsible for the destruction of many potentially infectious pathogens. A key event in the destruction process is the localised production of highly reactive molecular species by white blood cells as they engulf the pathogens. This work aims to identify the role of a molecule that is known to be physically associated with the structures formed during the engulfment process and we predict is important for production of reactive molecular species; called p40Phox.

Summary

unavailable
Committee Closed Committee - Biochemistry & Cell Biology (BCB)
Research TopicsImmunology
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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