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Award details
Function and regulation of the imprinted gene cluster on mouse distal chromosome 7 and human 11p15.5
Reference
BBS/E/B/0000C214
Principal Investigator / Supervisor
Professor Wolf Reik
Co-Investigators /
Co-Supervisors
Institution
Babraham Institute
Department
Babraham Institute Department
Funding type
Research
Value (£)
4,704,654
Status
Completed
Type
Institute Project
Start date
01/04/2005
End date
31/03/2012
Duration
84 months
Abstract
We inherit similar sets of genes from both our parents. A small number of genes are different in that one of the two copies is silenced; these are called ‘imprinted genes’. A number of genes which are important for growth and development of babies in the womb are imprinted. We are studying a particular collection of these genes, which are located in the same chromosomal region. We are studying the complex regulation of these genes and their effects on increasing or decreasing the size of the fetus as well as the role of mutations or other defects in fetal growth disorders and cancer.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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