BBSRC Portfolio Analyser
Award details
Mechanisms of axon degeneration
Reference
BBS/E/B/0000C200
Principal Investigator / Supervisor
Professor Michael Philip Coleman
Co-Investigators /
Co-Supervisors
Institution
Babraham Institute
Department
Babraham Institute Department
Funding type
Research
Value (£)
2,623,547
Status
Completed
Type
Institute Project
Start date
01/08/2003
End date
31/03/2012
Duration
104 months
Abstract
Nerve fibres, both in the brain and spinal cord (central nervous system) and in the rest of the body (peripheral nervous system) degenerate when they become injured or sick. It has generally been assumed that the mechanisms are different in injury and disease. However, we have shown that the mechanisms are far more related than previously thought, with at least one step in common that can be delayed by a genetic mutation. We aim to understand the pathways that this mutation delays, and to identify other common features of axon degeneration.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
Ageing, Neuroscience and Behaviour
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search