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Role of imprinted genes in regulation of energy homeostasis

Reference	BBS/E/B/0000C169
Principal Investigator / Supervisor	Dr Gavin Kelsey
Co-Investigators / Co-Supervisors
Institution	Babraham Institute
Department	Babraham Institute Department
Funding type	Research
Value (£)	2,060,816
Status	Completed
Type	Institute Project
Start date	01/10/2003
End date	31/03/2012
Duration	102 months

Abstract

We inherit similar sets of genes from both our parents. A small number of genes are different in that one of the two copies is silenced; these are called ‘imprinted genes’. This silencing appears to be an important means of controlling the activities of these genes and seems to be important in helping to control some of our body’s key processes, such as regulating food intake, blood sugar levels and the amount we store as fat. Because imprinted genes have only one active copy, it is particularly important that we understand how these genes function, how their activity is vulnerable to effects of nutrition or the environment, and what consequences they have on health and well-being.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	Ageing, Diet and Health
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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