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Function and regulation of the imprinted gene cluster on mouse distal chromosome 7 and human 11p15.5
Reference
BBS/E/B/00001210
Principal Investigator / Supervisor
Professor Wolf Reik
Co-Investigators /
Co-Supervisors
Institution
Babraham Institute
Department
Babraham Institute Department
Funding type
Research
Value (£)
219,388
Status
Completed
Type
Institute Project
Start date
01/04/2004
End date
31/03/2005
Duration
12 months
Abstract
A number of genes which are important for growth and development of babies in the womb are imprinted, that is only the paternal or the maternal gene is effective. We are studying a particular collection of these genes, which is located in the same chromosomal place. We are studying the complex regulation of these genes and their effects on increasing or decreasing the size of the fetus, both in mouse models and in humans where mutations or other defects in them are linked to fetal growth disorders and cancer.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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