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Neural and behavioural characterization of novel brain expressed imprinted genes
Reference
BBS/E/B/00001208
Principal Investigator / Supervisor
Dr Lawrence Wilkinson
Co-Investigators /
Co-Supervisors
Institution
Babraham Institute
Department
Babraham Institute Department
Funding type
Research
Value (£)
184,720
Status
Completed
Type
Institute Project
Start date
01/02/2004
End date
28/02/2005
Duration
13 months
Abstract
The project is a Synergy collaboration between the Neurobiology (Lawrence Wilkinson) and Developmental Genetics (Wolf Reik, Gavin Kelsey) programmes and will look at two new imprinted genes, Nap1/5 and Peg13, in terms of brain function and behaviour. These novel imprinted genes (present on mouse chromosomes 6 and 15) were discovered by the Kelsey group at the Babraham Institute using screening methods that exploit characteristic molecular features of this class of gene. The practical work will focus on mapping the fine distribution of these genes in the brain and assessing the behavioural effects of interfering with their function. Additionally, this project will also examine evidence for the existence of novel imprinted genes on the X-chromosome.
Summary
unavailable
Committee
Closed Committee - Animal Sciences (AS)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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