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Allosteric modulation of vertebrate adrenergic receptors

ReferenceBBS/E/B/00001195
Principal Investigator / Supervisor Dr Peter Evans
Co-Investigators /
Co-Supervisors
Institution Babraham Institute
DepartmentBabraham Institute Department
Funding typeResearch
Value (£) 168,630
StatusCompleted
TypeInstitute Project
Start date 01/04/2003
End date 28/02/2005
Duration23 months

Abstract

Vertebrate adrenergic G-protein coupled receptors control the functioning of many systems in the body including the heart, peripheral blood vessels and the brain. It is assumed that such receptors are activated by the catecholamines noradrenaline and adrenaline. This project aims to see if the signalling properties of such receptors can be modified by the binding of modulatory molecules other than catecholamines. It will increase our basic knowledge of how adrenergic neurones talk to the cells with which they interact.

Summary

unavailable
Committee Closed Committee - Biochemistry & Cell Biology (BCB)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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