Award details

The relationship between TSE infectivity in sheep blood and lymphiod tissues, PrP genotype, and disease pathogenesis

ReferenceBBS/E/A/00001658
Principal Investigator / Supervisor Dr Eleanor Fiona Houston
Co-Investigators /
Co-Supervisors
Institution The Roslin Institute
DepartmentThe Roslin Institute Department
Funding typeResearch
Value (£) 33,871
StatusCompleted
TypeInstitute Project
Start date 01/04/2007
End date 31/03/2010
Duration36 months

Abstract

The project objectives are to develop more sensitive assays for PrPsc and infectivity in sheep blood, to determine the distribution of infectivity and / or PrPsc among subsets of sheep leukocytes, to determine the degree of correlation between TSE infectivity in lymphoid tissues and blood and to determine whether PrP genotype influences the levels of PrP protein expressed in sheep tissues.

Summary

unavailable
Committee Closed Committee - Agri-food (AF)
Research TopicsAnimal Health, TSEs (transmissible spongiform encephalopathies)
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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