Award details

High-performance QTL analysis via the grid (GridQTL)

Reference	BBS/B/16976
Principal Investigator / Supervisor	Professor Christopher Haley
Co-Investigators / Co-Supervisors	Professor Dirk De Koning
Institution	The Roslin Institute
Department	Genetics and Genomics
Funding type	Research
Value (£)	249,301
Status	Completed
Type	Research Grant
Start date	20/05/2005
End date	19/05/2008
Duration	36 months

Abstract

We will develop and implement a grid-based platform for robust and rapid multiple trait mapping of interacting quantitative trait loci in simple and complex pedigrees, with a particular focus on high-throughput QTL analysis of gene expression array data (mapping eQTL). The existing QTL Express Java Servlet platform will be transformed to be grid compatible with novel methods for flexible workflow management and resource allocation, adding data persistence and detached execution. New approaches for multitrait and multiple QTL analysis in structured populations will be developed and tested using real and simulated data and implemented on the grid-base platform. This development on the grid provides an essential core component of a future integrated system incorporating genetic, phenotypic, transcription and comparative information to allow prediction from sequence to consequence. (Joint with BBS/B/1695X).

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	Animal Health, Technology and Methods Development
Research Priority	X – Research Priority information not available
Research Initiative	Bioinformatics and E Science Programme II (BEP2) [2003-2004]
Funding Scheme	X – not Funded via a specific Funding Scheme

Associated awards:

BBS/B/1695X High-performance QTL analysis via the grid (GridQTL)

BBS/B/16976/2 High-performance QTL analysis via the grid (GridQTL)

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