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E-scientific reconstruction of the pacemaking and conduction system of the heart

Reference	BBS/B/1678X
Principal Investigator / Supervisor	Professor Mark R. Boyett
Co-Investigators / Co-Supervisors	Professor Min Chen, Professor Jules Hancox, Professor Arun Holden, Professor John Tucker, Professor Henggui Zhang
Institution	The University of Manchester
Department	Medical and Human Sciences
Funding type	Research
Value (£)	626,640
Status	Completed
Type	Research Grant
Start date	01/09/2005
End date	31/08/2010
Duration	60 months

Abstract

The heart's pacemaking and conduction system plays important roles in initiation and control of cardiac rhythms. Understanding the functions of this system requires powerful computational tools to integrate and visualise experimental data obtained at many levels (e.g. functional, histological, molecular). We intend to develop such tools (parallel computing algorithms, Grid/Remote enabled visualisation) to reconstruct the pacemaking and conduction system at cell, tissue and organ levels. This will be a major contribution to the generation of a virtual heart and, furthermore, the tools developed will help provide a solid platform for e-Scientific reconstruction of other biological systems in silico.

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	Technology and Methods Development
Research Priority	X – Research Priority information not available
Research Initiative	Bioinformatics and E Science Programme II (BEP2) [2003-2004]
Funding Scheme	X – not Funded via a specific Funding Scheme

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