Award details

Integration of GRID-based post-genomic data resources through Bayesian calibration of biological simulators

Reference	BBS/B/16550
Principal Investigator / Supervisor	Professor Darren Wilkinson
Co-Investigators / Co-Supervisors	Professor R J Boys, Professor Tom Kirkwood
Institution	Newcastle University
Department	Mathematics and Statistics
Funding type	Research
Value (£)	351,851
Status	Completed
Type	Research Grant
Start date	01/01/2005
End date	31/12/2008
Duration	48 months

Abstract

The primary aim of the project is to capitalise on the development of GRID-based modelling and simulation resources such as BASIS by building a higher level computational GRID facility designed for integration of multiple post-genomic data resources. This facility, based on state-of-the-art Bayesian calibration techniques, will call upon GRID-based biological simulators for forward simulation whilst solving the inverse problems facilitated by data integration internally. Thus the project will provide a powerful new tool for the academic community that will enable inferences to be made about parameters and relationships within large network models of biochemical pathways and cell signalling systems.

Summary

unavailable

Committee	Closed Committee - Engineering & Biological Systems (EBS)
Research Topics	Systems Biology, Technology and Methods Development
Research Priority	X – Research Priority information not available
Research Initiative	Bioinformatics and E Science Programme II (BEP2) [2003-2004]
Funding Scheme	X – not Funded via a specific Funding Scheme

I accept the terms and conditions of use (opens in new window)

export PDF file

back to list new search