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Mechanisms of redifferentiation of somatic stem cells for tissue engineering
Reference
BBS/B/15384
Principal Investigator / Supervisor
Professor Ian Mackenzie
Co-Investigators /
Co-Supervisors
Professor Harshad Navsaria
Institution
Queen Mary University of London
Department
Sch of Medicine & Dentistry
Funding type
Research
Value (£)
209,206
Status
Completed
Type
Research Grant
Start date
02/06/2004
End date
01/07/2007
Duration
37 months
Abstract
Several reports now indicate that somatic epithelial stem cells possess a large degree of phenotypic plasticity. The proposed work will examine the actions of signalling mechanisms arising from mesenchymal cells and their secreted products that lead to re-differentiation of epithelia stem cells. The work aims to develop methods for generating stem cells that produce defined epithelial phenotypes for tissue engineering.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
Stem Cell Science and Engineering Initiative (SCE) [2003-2005]
Funding Scheme
X – not Funded via a specific Funding Scheme
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