Award details

Characterisation of a novel adult stem cell population from hair follicle dermistesting functional competency

ReferenceBBS/B/14558
Principal Investigator / Supervisor Professor Colin Jahoda
Co-Investigators /
Co-Supervisors
Dr Nicholas Hole
Institution Durham University
DepartmentBiological and Biomedical Sciences
Funding typeResearch
Value (£) 289,663
StatusCompleted
TypeResearch Grant
Start date 31/01/2005
End date 30/01/2008
Duration36 months

Abstract

We have evidence that adult hair follicle dermis contains mesenchymal stem cells and multipotent progenitor cell populations. This project will use culture, labelling and microarray techniques to characterise these cells, and to investigate their origin and stability during embryonic follicle development. We plan to test the extent to which adult follicle dermal stem cells can participate in organ function, by combining them with morulae derived from mice with genetic deficiencies in specific blood, brain, or lens cell populations. Using human specimens we will compare the stem cell capabilities of follicular and interfollicular dermal stem cells - two highly accessible sources with therapeutic potential.

Summary

unavailable
Committee Closed Committee - Genes & Developmental Biology (GDB)
Research TopicsX – not assigned to a current Research Topic
Research PriorityX – Research Priority information not available
Research Initiative Stem Cell Science and Engineering Initiative (SCE) [2003-2005]
Funding SchemeX – not Funded via a specific Funding Scheme
terms and conditions of use (opens in new window)
export PDF file