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Bioinformatic analyses of neuronal ensemble recordings and the evolution of genomic imprinting

Reference	BBS/B/13896
Principal Investigator / Supervisor	Professor Keith Kendrick
Co-Investigators / Co-Supervisors	Professor Wolf Reik
Institution	Babraham Institute
Department	Babraham Institute Department
Funding type	Research
Value (£)	267,405
Status	Completed
Type	Research Grant
Start date	06/07/2004
End date	05/07/2007
Duration	36 months

Abstract

The application of informatics tools to the analysis of biological function is one of the most important requirements for the progress of biological, pharmaceutical and biomedical sciences. However, we lack the necessary tools, expertise and resources to analyse multi-factorial measurements of cell and organism function and to exploit genomic and proteomic information. The main aims of the two bioinformatics projects here are: (i) to develop new tools for the statistical analysis and display of multiarray single cell electrophysiological recording data from sensory systems in the mammalian brain in order to establish fundamental principles of neural encoding and (ii) to use a bioinformatics approach using comparative sequence information to investigate evolutionary origins of the development and functions of imprinted genes.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Bioinformatics and E Science Programme II (BEP2) [2003-2004]
Funding Scheme	X – not Funded via a specific Funding Scheme

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