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Genetical genomics: bioinformatics for high throughput characterisation of interacting loci controlling gene-expression

Reference	BBS/B/13802
Principal Investigator / Supervisor	Professor Christopher Haley
Co-Investigators / Co-Supervisors	Dr Andrew Law
Institution	The Roslin Institute
Department	Genetics and Genomics
Funding type	Research
Value (£)	269,877
Status	Completed
Type	Research Grant
Start date	01/06/2004
End date	31/08/2007
Duration	39 months

Abstract

This project will develop and implement tools for the detection of interacting genomic loci affecting gene-expression. Mapping approaches will be extended to deal with the tens of thousands of traits recorded in gene expression studies, requiring a high level of parallelisation and high performance computing. Approaches will be tested on expression data from more than 12,000 genes from recombinant inbred lines of mice and subsequently expanded to outbred livestock populations including the Institute advanced intercross line of poultry. The project will stimulate novel livestock research within the Institute and deliver a set of bioinformatic tools for genetical genomics that will form the basis of future projects in the eScience arena.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Bioinformatics and E Science Programme II (BEP2) [2003-2004]
Funding Scheme	X – not Funded via a specific Funding Scheme

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