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Map kinase signalling to the plant cell cycle: an integrated functional genomic approach

ReferenceBBS/B/13268/2
Principal Investigator / Supervisor Professor James Murray
Co-Investigators /
Co-Supervisors
Institution Cardiff University
DepartmentSchool of Biosciences
Funding typeResearch
Value (£) 36,926
StatusCompleted
TypeResearch Grant
Start date 01/01/2009
End date 30/06/2009
Duration6 months

Abstract

Perception of external signals impacts on the plant cell cycle to control growth and developmental responses by unknown mechanisms. Members of the 120 Arabidopsis MAP kinase signalling components, with largely unknown functions, are likely to play key roles. We will use a unique custom microarray distinguishing all Arabidopsis MAP kinases and cell cycle genes to (1) analyse the effects of external treatments triggering a variety of hormonal, stress and environmental cues; (2) profile existing plants where all MAP kinase pathways are genetically modified by knockout or constitutive activation of all 10 MAPKKs and hence link pathways and signals to the cell cycle. Detailed analysis of key controllers of the cell cycle will finally provide a mechanism how MAPK signalling pathways regulate the cell cycle in Arabidopsis. (Joint with BBS/B/13314).

Summary

unavailable
Committee Closed Committee - Plant & Microbial Sciences (PMS)
Research TopicsPlant Science
Research PriorityX – Research Priority information not available
Research Initiative X - not in an Initiative
Funding SchemeX – not Funded via a specific Funding Scheme
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