Award details

Map kinase signalling to the plant cell cycle: an integrated functional genomic approach

Reference	BBS/B/13268
Principal Investigator / Supervisor	Professor James Murray
Co-Investigators / Co-Supervisors
Institution	University of Cambridge
Department	Institute of Biotechnology
Funding type	Research
Value (£)	186,778
Status	Completed
Type	Research Grant
Start date	01/08/2004
End date	31/12/2008
Duration	53 months

Abstract

Perception of external signals impacts on the plant cell cycle to control growth and developmental responses by unknown mechanisms. Members of the 120 Arabidopsis MAP kinase signalling components, with largely unknown functions, are likely to play key roles. We will use a unique custom microarray distinguishing all Arabidopsis MAP kinases and cell cycle genes to (1) analyse the effects of external treatments triggering a variety of hormonal, stress and environmental cues; (2) profile existing plants where all MAP kinase pathways are genetically modified by knockout or constitutive activation of all 10 MAPKKs and hence link pathways and signals to the cell cycle. Detailed analysis of key controllers of the cell cycle will finally provide a mechanism how MAPK signalling pathways regulate the cell cycle in Arabidopsis. (Joint with BBS/B/13314).

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	Plant Science
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

Associated awards:

BBS/B/13268/2 Map kinase signalling to the plant cell cycle: an integrated functional genomic approach

BBS/B/13314 MAP kinase signalling to the plant cell cycle: an integrated functional genomic approach

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