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The root of the eukaryote tree based on nuclear -encoded mitochondrial proteins
Reference
BBS/B/12601
Principal Investigator / Supervisor
Professor Sandra Baldauf
Co-Investigators /
Co-Supervisors
Institution
University of York
Department
Biology
Funding type
Research
Value (£)
253,290
Status
Completed
Type
Research Grant
Start date
04/10/2004
End date
03/01/2008
Duration
39 months
Abstract
The root of the eukaryote tree is one of the most fundamental questions in phylogeny. Currently, there are three radically different proposed roots based on very different types of data. I propose to test these roots using a data set of nuclear-encoded mitochondrial (NcMt) genes. We have identified 21 universal NcMt genes from all completely sequenced eukaryotic genomes. Preliminary phylogenetic analyses of these data indicate a balanced tree without characteristics generally associated with long-branch attraction, the artefact that plagues most attempts to root the eukaryote tree. We will assemble a data set of NcMt genes from a representative set of taxa including all major groups of eukaryotes. The work will involve a complementary wet lab-based and post genomic bioinformatic approaches.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
X - not in an Initiative
Funding Scheme
X – not Funded via a specific Funding Scheme
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