Award details

The TNF Receptor Family in Cutaneous Development and Pattering

Reference	BBS/B/12083
Principal Investigator / Supervisor	Dr Denis Headon
Co-Investigators / Co-Supervisors
Institution	The University of Manchester
Department	Life Sciences
Funding type	Research
Value (£)	158,704
Status	Completed
Type	Research Grant
Start date	31/08/2004
End date	30/08/2007
Duration	36 months

Abstract

This project aims to understand how multi-gene families coordinate vertebrate developmental processes. Three TNF receptor (TNFR) family members are implicated in controlling development of cutaneous appendages, such as hairs, feathers, glands, and scales, but functional evidence of their roles is lacking. This project will elucidate the roles of this receptor family in appendage development using feathers as a model. The role of each individual receptor will be determined, and the interactive relationships between receptor signalling pathways defined. These studies will build a picture of the signalling network that controls appendage formation and insight into the emerging roles of TNFRs in vertebrate development.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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