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Analysis of the function of the ATR13 avirulence protein from Peronospora parasitica (AT)

Reference	BBS/B/11214
Principal Investigator / Supervisor	Professor James Beynon
Co-Investigators / Co-Supervisors	Dr Rebecca Allen
Institution	University of Warwick
Department	Warwick HRI
Funding type	Research
Value (£)	256,718
Status	Completed
Type	Research Grant
Start date	01/03/2004
End date	28/02/2007
Duration	36 months

Abstract

Understanding the role of pathogenicity factors in establishing disease on plants or eliciting plant defence is a major focus of current work in plant pathology. In a screen to clone pathogenicity factors from the Arabidopsis pathogen Peronospora parasitica (AT) we have cloned the avirulence gene ATR13. In this project we propose to identify the plant target of ATR13 using the yeast two-hybrid system and co-immunoprecipitation. As we have cloned the complementary resistance gene, RPP13, from Arabidopsis we will determine if the protein products of these two genes interact directly. We will also study the localisation of the ATR13 protein in the plant and determine if alleles of ATR13 interact with the same targets as ATR13 and are also recognised by alleles of RPP13.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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