Award details

Plant growth and enzymes of polysaccharide synthesis in the Golgi apparatus

Reference	BBS/B/10684
Principal Investigator / Supervisor	Professor Paul Dupree
Co-Investigators / Co-Supervisors	Professor Kathryn Lilley
Institution	University of Cambridge
Department	Biochemistry
Funding type	Research
Value (£)	375,821
Status	Completed
Type	Research Grant
Start date	21/10/2004
End date	20/10/2007
Duration	36 months

Abstract

The aim is to link synthesis of specific polysaccharides to plant growth or development. The approach will be to identify carbohydrate active enzymes of the Golgi apparatus though multi-dimensional LC-MS/MS combined with quantitative analysis of subcellular fractions. The function of selected glycosyltransferases will be investigated through analysis of cell wall polysaccharides and of growth and morphology in Arabidopsis mutants. It is expected that changes in expression of some of the proteins identified will result in altered growth and altered structure or quantity of cell wall polysaccharides. This will provide gene candidates for future studies on glycosyltransferase activity, the role of cognate genes in crop plants, and the function of polysaccharides in plant growth, development, differentiation and pathogen resistance.

Summary

unavailable

Committee	Closed Committee - Plant & Microbial Sciences (PMS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Proteomics and Cell Function (PCF) [2003-2004]
Funding Scheme	X – not Funded via a specific Funding Scheme

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