Award details

Defining the meiotic proteome of higher plants

Reference	BBS/B/09414
Principal Investigator / Supervisor	Professor Chris Franklin
Co-Investigators / Co-Supervisors	Professor Glyn Jenkins, Dr G Jones, Dr Jonathan Paul Ride
Institution	University of Birmingham
Department	Sch of Biosciences
Funding type	Research
Value (£)	309,221
Status	Completed
Type	Research Grant
Start date	01/05/2004
End date	30/06/2007
Duration	38 months

Abstract

The aim of this project is to define the plant meiotic proteome with particular reference to the synaptonemal complex. This is a key meiotic structure that is thought to play a central role in regulating the frequency and distribution of homologous recombination events. We propose to analyse and compare the organisation, the synaptonemal complex from Brassica, Arabidopsis and rye using a combination of proteomics and molecular cytogenetics. A key objective will be to investigate the biosynthesis of the complex during prophase I and to establish its functional relationship with the proteins and complexes that are essential for pairing and recombination of homologous chromosome during meiosis.

Summary

unavailable

Committee	Closed Committee - Genes & Developmental Biology (GDB)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	Proteomics and Cell Function (PCF) [2003-2004]
Funding Scheme	X – not Funded via a specific Funding Scheme

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