BBSRC Portfolio Analyser
Award details
Features of maize imprinted genes which mark them for epigenetic modification and subsequent differential expression in the endosperm
Reference
BBS/B/07853
Principal Investigator / Supervisor
Professor Hugh Dickinson
Co-Investigators /
Co-Supervisors
Institution
University of Oxford
Department
Plant Sciences
Funding type
Research
Value (£)
355,018
Status
Completed
Type
Research Grant
Start date
01/02/2004
End date
31/01/2007
Duration
36 months
Abstract
Imprinted genes involved in development of the triploid endosperm of maize are transcribed only from the male, or the female alleles. This monoallelic expression is regulated through epigenetic marks applied during development. These imprinting marks (IMs) include methylation changes and histone modifications. Using previously identified imprinted genes, the nature of the IMs that direct both transient and constitutive monoallelic expression from either male or female alleles will be investigated, and IM status determined during gametogenesis, in the central cell and during endosperm development. Features of imprinted sequences, which identify them for the application of IMs, will be explored using a transgenic approach. Data from these studies will enable the testing of a model for imprinting in plants, which differs radically from that proposed for animals.
Summary
unavailable
Committee
Closed Committee - Genes & Developmental Biology (GDB)
Research Topics
X – not assigned to a current Research Topic
Research Priority
X – Research Priority information not available
Research Initiative
Integrated Epigenetics (EPI) [2003]
Funding Scheme
X – not Funded via a specific Funding Scheme
I accept the
terms and conditions of use
(opens in new window)
export PDF file
back to list
new search