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Identification and characterisation of habituation mutants in Drosophila

Reference	BBS/B/06954
Principal Investigator / Supervisor	Professor Cahir O'Kane
Co-Investigators / Co-Supervisors
Institution	University of Cambridge
Department	Genetics
Funding type	Research
Value (£)	349,066
Status	Completed
Type	Research Grant
Start date	01/03/2004
End date	29/02/2008
Duration	48 months

Abstract

Habituation is a decrement in the response to a stimulus on repeated presentation of the stimulus, and is a behavioural adaptation that is required for selective attention, prevents inappropriate responses to repeated stimuli, and is a simple form of learning. We have previously established a semiautomated version of habituation of an olfactory jump response in Drosophila. To understand better the cellular mechanisms of habituation, we initiated a small screen for mutations affecting this behaviour, and identified at least one novel robust mutant. Here we wish to study the molecular and cellular role of the affected protein. We also wish to extend the mutant screen, to identify and understand additional components of the molecular mechanisms.

Summary

unavailable

Committee	Closed Committee - Animal Sciences (AS)
Research Topics	X – not assigned to a current Research Topic
Research Priority	X – Research Priority information not available
Research Initiative	X - not in an Initiative
Funding Scheme	X – not Funded via a specific Funding Scheme

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